A Study of Hepatic Hemodynamics in the Dog.

• The purpose of this work was to study in detail some of the factors related to the rise in portal vein pressure which accompanies sympathetic nerve stimulation. These hemodynamic factors were studied by observing the changes in hepatic artery and portal vein vascular resistances noted during controlled perfusion of the liver in vivo. Initially, the pressure-flow characteristics of the hepatic artery and portal vein vasculature and the interrelationship between the two vessels were studied in the nonstimulated state; then these same parameters were restudied during and following stimulation of sympathetic innervarion.